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Dr. Rodrigo Zamith Cunha: “Distribution of endocannabinoid system receptors in the equine hoof: dysregulation as a potential therapeutic target for laminitis.”

Dear Readers, New Publication Alert!


I’m thrilled to share our latest research published in Histochemistry and Cell Biology, entitled


“Distribution of endocannabinoid system receptors in the equine hoof: dysregulation as a potential therapeutic target for laminitis.”


This work is the result of four years of dedication, research, and teamwork, driven by a passion to improve the understanding and treatment of laminitis in horses. 


Key takeaways:


We characterized, for the first time, the distribution of cannabinoid receptors CB1, CB2, and GPR55 in healthy and laminitic hoof lamellae. These receptors are not only present but also dysregulated in laminitis, suggesting new opportunities for therapeutic approaches using cannabinoids.


Targeting the endocannabinoid system could represent a promising strategy to support healing and reduce inflammation in equine hoof diseases. Despite the relevance of our findings, otherlimitations must be acknowledged, know more in the full text. 




This study was inspired by Hope, a very special patient whose journey motivated me to pursue this line of research. I am deeply grateful to Hope for sparking this scientific path, to my team at the Equine Hospital during my internship, and to all my colleagues and mentors who supported me throughout these years.



Our findings open new doors to integrative and innovative treatments for one of the most challenging equine conditions, and may explain the clinical outcome I had.



Read the full article here: https://lnkd.in/d4NZ7yeg



A heartfelt thank you to my incredible co-authors, collaborators, and everyone who believed in this work!



 
 
 

Commenti


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“Balou, an 11 year old gelding, ridden by Andrew Hoy was unable to retain fitness. In April 2023 he was treated with EquiCeutica CBD and recovered his condition within 3 weeks with a successful return to international competition"

Nelson Pessoa, Olympic Equestrian and Trainer (Balou is now ridden by Germany's Michael Jung)

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